Cryo-EM Resources & Knowledge Base
Evidence-based guides and product comparisons to help you choose the right cryo-EM grid and optimize your sample preparation.
Product Comparisons
ANTcryo vs Quantifoil
Amorphous NiTi Alloy vs Holey Carbon
Side-by-side comparison of protein adsorption, beam-induced motion, self-wetting, and sample preparation workflow. Find out when ANTcryo outperforms the industry standard.
ANTcryo vs UltrAuFoil
Amorphous NiTi Alloy vs Pure Gold Foil
Both use gold grids for reduced beam-induced motion. But the support film material — amorphous NiTi alloy vs pure gold foil — makes a real difference in your workflow.
Grid Selection Guides
Choosing a Grid for SPA
What to consider when selecting a grid for single particle analysis: material, hole size, mesh count, and sample compatibility.
Coming SoonChoosing a Grid for Cryo-ET
Special considerations for cryo-electron tomography: grid flatness, FIB-milling compatibility, cell culture requirements, and support film durability.
Coming SoonTechnical Articles
5 Common Cryo-EM Grid Problems and How to Solve Them
Air-water interface issues, preferred orientation, beam-induced motion, and more.
Why Non-Carbon Support Films Are the Future of Cryo-EM
How amorphous alloy and gold support films are replacing traditional carbon films.
Air-Water Interface: The Silent Killer of Cryo-EM Samples
Understanding and mitigating protein denaturation at the air-water interface.
Research Publications
Over 100 peer-reviewed papers have been published using ANTcryo grids, including in Science, Cell, and Nature Methods.
Browse PublicationsHave Questions About Choosing a Grid?
Our team can help you select the right ANTcryo product for your specific sample and workflow.
Contact Our Team